As the name implies, a capsule is a solid or liquid drug (referred to as a core material) and is wrapped on the surface of the drug with a macromolecule substance or a copolymer (abbreviated as a capsular material) so as to be a translucent and closed package, and the appearance is generally granular or spherical. As a kind of packaging, capsules have been widely used in the pharmaceutical industry.
With the rapid development of the pharmaceutical industry, people's demand for capsule filling machines is increasing, and the quality requirements for pharmaceutical filling are also increasing. At present, the equipment of various industries is in the direction of full automation. Therefore, the following takes the Bosch automatic capsule filling machine GKF700 as an example to introduce to the majority of pharmaceutical companies how capsule filling is automated and then meets the requirements of pharmaceutical companies for fast, stable and hygienic requirements.
The automatic capsule filling machine GKF700 has a total of 12 stations. The specific process principle is:
1. The empty capsule is discharged from the capsule bucket and pushed through the capsule groove into the 1 station (sequencing station) in an orderly manner. This station uses a vacuum suction method to separate the capsule body up and down, and the capsule cap is on the upper module The capsule body is in the lower module and then goes into the 2 stations, these are usually the operator's monitoring stations.
2. After passing through the third transition station, the capsule cap and the capsule body enter the filling stations 4, 5, and 6. The filling station pushes the filled powder column (powder column) into the capsule body of the lower module. Usually, the powder filling is completed at the 5th station, the sheet medicine is filled in the 4th station, and the pellet medicine is filled in the 6th station.
3. After the transition station of the 7th station, the filled capsule enters the 8th station. This station can remove the failed capsules, including unseparated capsules, incorrectly inserted capsules or two capsule caps. Capsules. The purpose is to ensure that the packed capsules are filled correctly.
4. The 9th station is the positioning station where the machine aligns the top and bottom of the capsule. After the capsule is aligned up and down, it enters the sealing station of the 10th station. This station has a special ejector rod to reciprocate up and down. The device can be said to have completed the automatic filling and filling of capsules and powders.
5. The filled capsule comes to the 11th station, which is the capsule discharge station. The capsule is ejected or ejected using a fixed rod. The 12th station is a vacuum cleaner cleaning station, with an automatic purge unit to clean the upper and lower modules. Finally enter the next working cycle.
As far as the current domestic pharmaceutical market is concerned, most capsule filling equipments have the problems of filled powder splashing, poor filling accuracy, and the appearance of empty sac or bad sac. These problems will not only affect the quality of the products and the normal operation of the equipment, but more importantly they will cause huge losses to the pharmaceutical companies. The automatic capsule filling machine GKF700 can help pharmaceutical companies solve the above problems from the following aspects:
First of all, there are many factors that affect the powder spatter, such as: filling in a non-enclosed environment, the formability of the powder itself, the quality of the pressure filling device mold, and the stability of the equipment operation. The powder filling process of GKF700 is carried out in a completely enclosed environment, and the powder (pharmaceutical) is first pressed into a column shape, and then the pressured powder column is pushed into the space by a pushing device of the filling station. In the capsule.
Secondly, when the equipment is filled, it is measured with the same gauge (aperture), and the height control is used to control the filling amount of the powder. This kind of metering method has high precision, and it can reach filling accuracy within 1% error for many products. The device can also be equipped with an adjustable metering disc, so that it can be changed without a lot of disassembly. With a small amount of operation, the filling amount can be changed, and the rapid conversion of products of different specifications in a short cycle can be realized.
Not only that, GKF700 also introduced an online automatic weighing and detection system IPK system. The IPK system can record the filling deviation and quality status of any stage of the capsule production process, which further improves the quality and production efficiency of the capsule filling. For example, tens of thousands of capsules can be produced within 2 hours, among which a few are light or heavy and IPK can detect it. If necessary, the operator can stop and adjust according to the test data.
In addition, the automatic capsule filling machine has the following features:
1. Because a large number of molds are used, it is possible to quickly and simply realize production conversion of different specifications.
2. Standard sorting module to achieve automatic feeding and sorting of empty capsules;
3. The application of vacuum pump to automatically suck the product into the finished product bucket;
4. The main drive motor of the equipment adopts variable frequency control, and the production operation is divided into automatic mode and jog mode.
5.PLC program control system, touch-type operation panel to improve the safety and stability of production, maximize the production efficiency;
6. Fully enclosed production, safety and health, low noise, high speed, and high filling accuracy.
Source: Huayin
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